For those of us who have struggled with chronic fatigue and illness, the search for substances that might help us regain our energy and vitality may seem never-ending. Many of us have tried countless supplements and treatments, with maybe a few “hits” here and there, but often quite a few “misses.” In my own journey with Lyme disease and chronic fatigue, I have often struggled in trying to find natural treatments to help improve my energy level. However, when I learned about a supplement called Poly MVA a few months ago, and had the chance to experience its amazing effects, I knew I had found a definite “hit” in terms of an energy-promoting supplement!
Poly MVA is a unique combination of vitamins, minerals, and amino acids that supports cellular energy production, exerts antioxidant effects, and replaces nutrients that may have become depleted in the body due to chronic illness or certain health therapies. Two of the key ingredients in Poly MVA (also referred to as Palladium Alpha-lipoic acid Complex) are palladium, which is a mineral, and Alpha-lipoic acid, which is an antioxidant that is found in every cell of the body and is required for helping the body turn food into energy, as well as for combatting free-radical damage (Alpha-lipoic acid, 2014).
In scientific studies, Poly MVA has demonstrated a numerous fascinating health-promoting effects. In animal studies, Poly MVA has been found to elevate mitochondrial energy status in the brain. It accomplishes this by providing cofactors (vitamins, minerals, and amino acids) for enzymes that are needed to produce ATP (Ajith, Nima, Veena, Janardhanan, Antonawich, 2014). ATP is essentially the energy “currency” of our cells, and is needed to drive countless metabolic reactions. ATP is produced in the mitochondria, which are in turn located within our cells. Mitochondria act as energy factories. By providing the ingredients needed to fuel mitochondria and produce ATP, Poly MVA may have great implications for helping to reverse cellular energy deficits, and thus improve energy status throughout the body.
Poly MVA has also been shown to assist in DNA repair in response to injurious agents such as gamma-radiation (Menon, Krishnan, Nair, 2009). In day-to-day life, gamma-radiation is encountered in the form of radiation treatment for cancer. Gamma-radiation is also produced by nuclear reactors that create nuclear energy. Unfortunately, many of us are exposed to detrimental radiation more often than we might realize, and a natural product that can help us repair that damage could be very beneficial.
In addition to its ability to increase ATP production and repair DNA, Poly MVA may also help alleviate hyperglycemia, and thus be helpful for diabetics and people who struggle with blood sugar control. In addition to lowering blood sugar levels, Poly MVA simultaneously restores antioxidant levels; antioxidant depletion is a phenomenon that occurs in conjunction with hyperglycemia because hyperglycemia creates free radicals, so a substance that can target both problems at once is certainly valuable (Sudheesh, Janardhanan, Krishnan, 2011).
Finally, Poly MVA increases levels of antioxidant enzymes in the body, especially in the liver. In a study in which rats were exposed to gamma-radiation, and experienced a subsequent decrease in antioxidant levels within hepatic (liver) cells, administration of Poly MVA led to a restoration of antioxidant enzyme levels.
The particular antioxidant enzymes that were measured included Glutathione, Catalase, and Superoxide Dismutase. An increase in these specific antioxidant enzymes can improve liver function (El-Marakby, Selim, Desouky, Ashry, Sallam, 2013). By improving liver function, we can also help fortify our bodies against bodily stresses, including chronic infections. I’m sure all of our livers could use a little TLC, and Poly MVA can help us out in that regard!
In terms of administration, Poly MVA can be taken into the body either through an IV or orally as a liquid supplement. I have personally received a Poly MVA IV twice, and responded quite well to it. However, it can be difficult to find practitioners who offer Poly MVA IVs, so an oral supplement may be a more convenient and affordable solution.
Poly MVA clearly offers a lot of promise in terms of health benefits for people who may be dealing with chronic illness. It certainly has helped me in my process of recovering from Lyme disease. For anyone who feels that they have exhausted their options when it comes to finding solutions for fatigue, but also for people who want to fortify their bodies and promote optimal health, Poly MVA may be a wonderful addition to your health protocol!
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Ajith, T.A., Nima, N., Veena, R.K., Janardhanan, K.K., Antonawich, F. (2014). Effect of palladium α-lipoic acid complex on energy in the brain mitochondria of aged rats. Alternative Therapies in Health and Medicine. 20(3): 27-35. Retrieved from http://www.ncbi.nlm.nih.gov/pubmed/24755568.
Alpha-lipoic Acid. (2014). University of Maryland Medical Center [online]. Retrieved from http://umm.edu/health/medical/altmed/supplement/alphalipoic-acid.
El-Marakbya, S.M., Selima, N.S., Desoukya, O.S., Ashrya, H.A., Sallamb, A.M. (2013). Effects of Poly-MVA on the rheological properties of blood after in-vivo exposure to gamma radiation. Journal of Radiation Research and Applied Sciences, 6(2): 21-30. Retrieved from http://www.sciencedirect.com/science/article/pii/S1687850713000046.
Menon, A., Krishnan, C.V., Nair, C.K.K. (2009) Protection from gamma-radiation insult to antioxidant defense and cellular DNA by POLY-MVA, a dietary supplement containing palladium lipoic acid formulation. International Journal of Low Radiation, 6(3): 248-262. Retrieved from http://www.inderscienceonline.com/doi/abs/10.1504/IJLR.2009.028892.
Ramachandran, L., Krishnan, C.V., Nair, C.K. (2010). Radioprotection by alpha-lipoic acid palladium complex formulation (POLY-MVA) in mice. Cancer Biotherapy and Radiopharmaceuticals, 25(4): 395-399. http://www.ncbi.nlm.nih.gov/pubmed/20701542.
Sudheesh, N.P., Janardhanan, K.K., Krishnan, C.V. (2011). Palladium-α-lipoic acid complex attenuates alloxan-induced hyperglycemia and enhances the declined blood antioxidant status in diabetic rats. Journal of Diabetes, 3(4): 293-300. Retrieved from http://onlinelibrary.wiley.com.libproxy.bridgeport.edu/doi/10.1111/j.1753-0407.2011.00142.x/abstract.
About the author: Lindsay has her Bachelors of Science in Biomedical Science, with an Emphasis in Nutrition, from National University of Health Sciences. When she is not studying nutrition or researching and writing, Lindsay enjoys working out, rock climbing, hiking, skiing, and having adventures outdoors. She is also quite passionate about her camera and taking nature photography. You can read more about Lindsay’s Lyme disease experience, as well read all her latest thoughts and research on health, by visiting her blog, Rock On Nutrition, athttps://rockonnutrition.me/.