TMG Pro Tablets - 1000 mg, 120 tablets

SKU: PH568

Sale price

Regular price $16.57
( / )

97% would recommend this product (32 votes)

  • Have questions about this product?
    Ask one of our experts.
  • click here

Free Nutritional Advisor

Free Nutritional Advisor

A methyl donor that complements NMN and supports heart health and liver detoxification.

  • Supports liver detoxification¬†
  • Supports cardiovascular health¬†
  • Promotes healthy homocysteine levels¬†
  • Supports cellular health¬†

View Certificate of Analysis

Research-Supported Benefits:

Supports Cellular Health. TMG is an amino acid that supports the body's methylation processes. Methylation is essential for numerous important cellular functions, including cell division, energy production and producing antioxidants to fight oxidative stress.1

Supports Detoxification. The donation of methyl groups by TMG is critical for healthy liver function and detoxification.1

Supports Cardiovascular Health. TMG may decrease blood levels of homocysteine, an amino acid that is linked to poor heart health and blood vessel damage when elevated.2


1. Arumugam MK, Paal MC, Donohue TM Jr, Ganesan M, Osna NA, Kharbanda KK. Beneficial Effects of Betaine: A Comprehensive Review. Biology (Basel). 2021;10(6):456. Published 2021 May 22. doi:10.3390/biology10060456 

2. McRae MP. Betaine supplementation decreases plasma homocysteine in healthy adult participants: a meta-analysis. J Chiropr Med. 2013;12(1):20-25. doi:10.1016/j.jcm.2012.11.001 doi:10.1016/j.jcm.2012.11.001 

  • Trimethylglycine (TMG), also known as betaine anhydrous, is an amino acid that supports the body's methylation processes.¬†
  • Methylation is a fundamental biochemical process in which one carbon atom and three hydrogen atoms (CH3) are transferred from one molecule to another.¬†
  • Methylation is responsible for numerous important bodily functions, such as cell division, cellular energy production, clearing histamine, metabolism, DNA expression (epigenetics), forming neurotransmitters and producing free radical-scavenging antioxidants.¬†
  • Our bodies contain a ‚Äúmethyl pool‚ÄĚ of CH3 that is available whenever needed. As long as we have enough methyl groups stored in the pool, methylation typically is not a problem. However, there are a couple of things that may contribute to the depletion of the body's methyl pool.¬†
  • MTHFR Variants - Methylenetetrahydrofolate reductase (MTHFR) is a gene with common mutations that can interfere with the methylation process, causing high levels of homocysteine (a known risk factor in heart health conditions) in the blood and low folate levels. Up to 40% of the population may have one or both genetic mutations.¬†
  • Aging and Epigenetics - Methylation of DNA plays a crucial role in epigenetics, switching different sequences of your genetic material on and off as needed. The body's methylation ability and subsequent DNA expression are known to decline with age. Anti-aging researchers think these changes in DNA expression may be a contributing factor to many age-related diseases.¬†
  • NMN Supplementation and Methylation Support. When taken as a supplement, NMN may require the use of methyl groups to help facilitate the conversion of NAD+ in your cells, thereby activating sirtuin genes and promoting longevity. Although there is currently no evidence suggesting NMN‚Äôs natural methylation process depletes the methyl pool, many top anti-aging experts suggest that safeguarding against methyl depletion may be a wise proactive step to augment your NMN intake.¬†
Supplement Facts
Serving Size: 1 Tablet
Servings Per Container: 120
Amount Per Serving %DV
Trimethylglycine (TMG) (Betaine Anhydrous) 1 g (1000 mg) †
† Daily Value (DV) not established
  • OTHER INGREDIENTS: Cellulose, stearic acid (vegetable source), croscarmellose sodium, magnesium stearate (vegetable source).
  • DOES NOT CONTAIN: Dairy, egg, soy, wheat, gluten, corn, fish, shellfish, tree nuts, peanuts.
  • SUGGESTED DAILY USE: Take 1-6 tablets daily, divided into 2 doses, or as recommended by your healthcare professional.
  • CAUTION: Not intended for use by pregnant or nursing women. Not formulated for use in children. If you have a medical condition or are taking medications, consult with your healthcare professional before using this product.
  • NOTE: Keep the bottle tightly closed at all times in between usage. Keep the freshness packet in bottle. This product is very sensitive to moisture/humidity which may affect product stability. Store in a cool dry place after opening. KEEP OUT OF REACH OF CHILDREN

Tablet Form. The tablet form of TMG Pro makes it easy to take.

Higher Dose. ProHealth’s TMG Pro contains 1,000 mg of TMG as Betaine Anhydrous, whereas other TMG supplements may contain just 750 mg.

Free of Unwanted Ingredients. TMG Pro doesn’t contain yeast, wheat, gluten, sugar, salt, dairy, eggs, peanuts, tree nuts, fish, shellfish, soy, corn, dye or preservatives.

Quality Manufacturing Practices. All of our products are manufactured in an FDA-registered, GMP-certified facility.

Third-Party Tested in the USA. Every batch is third-party tested in USA laboratories to ensure the highest quality, purity and potency. Certificates of Analysis are available.

which supplements are right for you?

Our Longevity Health Pros are just a text away with supplement & dietary answers, guidance & support.

Benefits +
How it Works +
How Ours is Better +
Label Information +
Benefits +
How it Works +
How Ours is Better +
Label Information +

Customer Reviews

Based on 78 reviews
Kenny O.

TMG Pro Tablets - 1000 mg, 120 tablets

John K.
No discernable difference

I’m about finished with my 120 tablet bottle. I’ve been taking 6 tablets daily. Although I want TMG to make a difference in my general health and vitality, I wouldn’t know if I took it or not. I desperately want it to make some uptick in my general health, but I would probably get more results just sucking on a sugar cube. I want it to make me feel a difference, but it just doesn’t. Very sorry, but I feel it has just been a waste.

Todd B.

Great Product!

Jennifer R.C.
Enhanced Energy

Definitely feel more energized overall and during workouts after taking TMG for a few weeks. Only downside is that the pill is very large and a bit difficult to swallow. Must take it with lots of water!

Derik W.
This Works!

Taken this supplement for 3 weeks and my Systolic and Diastolic BP has dropped 15 points.

Tim F.

Great stuff

George M.

Great Product

Linda R.

TMG Pro Tablets - 1000 mg, 120 tablets

Patricia F.
Hard to swallow

Very big. They get stuck on the way down. These would be better crushed inside a capsule so it would be easier to swallow. I have to crush them and dilute them in water.

Melissa E.

I haven't been taking this very long but I do feel more alert and less tired!

Frequently asked questions

It’s suggested to take 1-6 tablets daily divided into 2 doses, or as directed by a healthcare practitioner.
Keep the bottle tightly closed at all times in between usage. Keep the fresh packet in the bottle. This product is very sensitive to moisture/humidity which may affect product stability. Keep out of reach of children.
TMG is generally considered safe, but some people may experience digestive issues like cramping, bloating, nausea or diarrhea.