TMG Pro Powder (500 grams) (Bulk Powder) by ProHealth Longevity

SKU: PH556

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A Methyl Donor That Complements NMN Supplementation

  • Supports cardiovascular health*
  • Promotes healthy homocysteine levels*
  • Helps replenish the body's methyl pool*

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Supplement Facts
Serving Size: 1 Level Scoop
Servings Per Container: 500
Amount Per Serving %DV
Trimethylglycine (TMG) (Betaine Anhydrous) 1,000 mg
† Daily Value not established
REV. 01.22
  • Does Not Contain: Milk, egg, soy, gluten, wheat, fish, shellfish or tree nut ingredients.
  • Suggested Daily Use: Take 1 - 3 scoops daily, preferably with food, or as directed by a healthcare practitioner.
  • Note: This product is very sensitive to moisture/humidity which may affect product stability. Store in a cool dry place. Keep out of reach of children.
  • Caution: Consult physician if pregnant/nursing, taking medication, or have a medical condition.

Trimethylglycine (TMG), also known as betaine anhydrous, is an amino acid that supports the body's methylation processes. Methylation is a fundamental biochemical process in which one carbon atom and three hydrogen atoms (CH3) are transferred from one molecule to another. This process is responsible for numerous important bodily functions, such as:

  • Cell division
  • Cellular energy production
  • Clearing histamine
  • Metabolism
  • DNA expression (epigenetics)
  • Forming neurotransmitters
  • Producing free radical scavenging antioxidants

Our bodies contain a “methya l pool” of CH3 that is available whenever needed. As long as we have enough methyl groups stored in the pool, methylation typically is not a problem. However, there are a couple of things that may contribute to the depletion of the body's methyl pool.

  1. MTHFR Variants - Methylenetetrahydrofolate reductase (MTHFR) is a gene with common mutations that can interfere with the methylation process, causing high levels of homocysteine (a known risk factor in heart disease) in the blood and low folate levels. Up to 40% of the population may have one or both genetic mutations.

  2. Aging and Epigenetics - Methylation of DNA plays a crucial role in epigenetics, switching different sequences of your genetic material on and off as needed. The body's methylation ability and subsequent DNA expression is known to decline with age. Anti-aging researchers think these changes in DNA expression may be a contributing factor to many age-related diseases.*

NMN Supplementation and Methylation Support

When taken as a supplement, NMN may require the use of methyl groups to help facilitate the conversion of NAD+ in your cells, thereby activating sirtuin genes and promoting longevity. Although there is currently no evidence suggesting NMN’s natural methylation process depletes the methyl pool, many top anti-aging experts suggest that safeguarding against methyl depletion may be a wise proactive step to augment your NMN intake. TMG, the choice of many of those experts, is an excellent way to help support your body's ability to maintain an adequate methyl pool.

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Customer Reviews

Based on 41 reviews
Cheryl A.

Good quality supplement! I will order again. I recommend this product.

Steve R.

Good product

Cindi B.

I feel it assists my MNM to give me unbelievable energy. Can't get enough of this wonderful high

Garry B.
TMG, Great Product

TMG, Great Product

Yvette G.
TMG is a super-charger

Adding TMG to my NMN regimen has super-charged its effects!

Great Product

Best value around for TMG and fast delivery.

So far so good

I’ve been taking TMG in a combined formula for a month and recently switched to standalone single ingredient powder form, I’d like the higher dosage in the single ingredient formula mixes easily, and has no taste. I would recommend this if you’re looking for TMG..

Recommended one!

I've been taking NMN everyday, but before taking TMG, I felt more fatigue than before taking NMN. I didn't know the reason.
But since I started taking NMN and TMG together, I have felt many differences.
I felt a lot less tired and my head cleared up.
If you don't feel any effect from taking NMN, or if you feel more tired, I recommend taking this TMG together.

Marion K.
Does what it promises

Quick delivery excellent quality product

Richard A.
Loving My TMG

I started taking 1 gram of TMG powder in the morning about a month ago – and the results have been rather startling.

From the first day, (actually – from the first hours) I noticed a distinct difference in my energy and focus.

I also believe that my mental acuity has sharpened.

I feel more enthusiastic about work of all kinds and have also noticed increased vigor associated with my daily exercise.

All I can say is that it’s working for me!

Frequently asked questions

It’s suggested to take 1 - 3 scoops daily, preferably with food, or as directed by a healthcare practitioner.
This product is very sensitive to moisture/humidity which may affect product stability. Store in a cool dry place. Keep out of reach of children.
TMG is generally considered safe, but some people may experience digestive issues like cramping, bloating, nausea, or diarrhea.