Data indicate that women are two to three times as likely as men to develop Alzheimer’s disease, making this neurodegenerative condition a women’s health issue. The challenge of an aging population and women’s vulnerability to Alzheimer’s disease is reviewed. Strategies to prevent Alzheimer’s disease in women are discussed. These strategies include cognitive challenge and exercise, estrogen replacement therapy, anti-inflammatory agents, and antioxidants. Each of these strategies has been associated with a decreased risk of Alzheimer’s disease and could have a profound impact on the incidence of Alzheimer’s disease in the most vulnerable segment of the population, postmenopausal women.
Source: Int J Fertil Womens Med 1999 Jun-Aug;44(4):174-85
PMID: 10499738, UI: 99428084
(Department of Molecular Pharmacology and Toxicology, University of Southern California, Pharmaceutical Sciences Center, Los Angeles 90033, USA. )