[Note: Macroalbuminuria is excretion of high levels of albumin in the urine. The healthy kidney normally filters albumin out, so albuminuria is considered an indicator of poor kidney function – highly associated with cardiovascular disease.]
Background: The balance between the intake of animal and the intake of plant foods may influence renal vascular integrity as reflected by urinary albumin excretion.
Objective: We assessed cross-sectional associations between urinary albumin excretion and dietary patterns and intake of plant and animal foods.
Design: At baseline, diet (food-frequency questionnaire) and the urinary albumin-to-creatinine ratio (ACR; spot urine collection) were measured in 5,042 participants in the Multi-Ethnic Study of Atherosclerosis who were aged 45-84 years and were without clinical cardiovascular disease, diabetes, or macroalbuminuria (sex-adjusted ACR >or= 250).
We derived dietary patterns by principal components analysis. We also summed food groups to characterize:
Results: After adjustment for multiple demographic and lifestyle confounders:
Source: American Journal of Clinical Nutrition, Jun 2008;87:1825-1836. PMID: 18541574, by Nettleton JA, Steffen LM, Palmas W, Burke GL, Jacobs DR Jr. Division of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA. [E-mail: email@example.com]