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SPECT imaging brain perfusion using 99mTc-HMPAO was performed on a 38-yr-old women with
Lyme neuroborreliosis confirmed by autopsy. The patient had been suspected of spinocerebellar degeneration. Cerebral blood flow was diffusely decreased throughout cerebral cortices but cerebellar blood flow was not impaired, which indicated that the diagnosis was unlikely spinocerebellar degeneration. These findings suggested that brain perfusion SPECT provides useful information in diagnosing the patients with
Lyme neuroborreliosis, especially when spinocerebellar degeneration is included in the differential diagnosis.