Chronic Fatigue Syndrome (CFS) & nickel allergy

50 patients with chronic fatigue syndrome (CFS) and 73

controls were patch tested with 8 metal allergens. We found an

overrepresentation of allergies among the CFS patients, which

was not significant.

However, allergy to nickel occurred in

36% of patients in the CFS group and in 19% of subjects in the

control group (p<0.05). The high frequency of nickel allergy
was more noteworthy in females in the CFS group than among

female controls (52% and 24%, respectively, p<0.05). Similarly, in the males the figures were 14% and 9%. We
suggest that in vivo immunoactivation by ions of nickel, or

metal cross-reacting with nickel, could be an etiological

factor in CFS.

Marcusson JA, Lindh G, Evengard B

1 Star2 Stars3 Stars4 Stars5 Stars (No Ratings Yet)

Leave a Reply