Fibromyalgia (FM): more than just a musculoskeletal disease

Fibromyalgia is a common condition characterized by diffuse
musculoskeletal pain and fatigue. The syndrome is defined by
the presence of musculoskeletal tender points on physical
examination. Additionally, persons with this syndrome have a
high incidence of headaches, ocular and vestibular complaints,
paresthesias, esophageal dysmotility, "allergic" symptoms,
irritable bowl syndrome, genitourinary symptoms and affective
disorders. Recent research has revealed a number of objective
biochemical, hormonal and neurotransmitter abnormalities
associated with fibromyalgia, making it a clearly identifiable
condition. These abnormalities may clarify our understanding
of the pathogenesis and treatment of fibromyalgia.
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Clauw DJ

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