Fibromyalgia syndrome (FM) & nonarticular tenderness in relatives of patients with FM

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nonarticular tenderness in relatives of patients with FM.
METHODS:
Thirty female patients with FM randomly chosen from 117 of
their close relatives (parents, brothers, sisters, children,
husbands) were assessed for nonarticular tenderness. A count
of 18 tender points was conducted by thumb palpation, and
tenderness thresholds were assessed by dolorimetry at 9 tender
sites. FM was diagnosed according to the 1990 American College
of Rheumatology criteria.
RESULTS: The prevalence of FM among
blood relatives of patients with FM was 26%, and among their
husbands 19%. FM prevalence in male relatives was 14%, and in
female relatives 41%. The mean tender point counts of male and
female young relatives was significantly higher than that of
controls: 6.1 vs 0.2 (p < 0.01), and 4.4 vs 0.4 (p < 0.01)
respectively. Similarly, adult relatives had considerably
higher mean tender point counts than controls: 4.0 vs 0.04 (p
< 0.01) and 10.3 vs 0.28 (p < 0.01) respectively, for males
and females.
CONCLUSION: Relatives of patients with FM have a
higher prevalence of FM and are more tender than the general
population, as recently reported and shown in a healthy
control group. This finding can be attributed to genetic and
environmental factors.

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