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Histologic demonstration of intradermal spirochetes in a patient with Lyme disease.

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Abstract

Spirochetal organisms were demonstrated histologically in skin biopsy specimens from a patient with
Lyme disease and erythema chronicum migrans. The patient responded rapidly to penicillin G benzathine administration. Convalescent serum contained a high titer of antibody to an lxodes dammini spirochete antigen. The finding of spirochetes in an erythema chronicum migrans lesion in a patient with clinical
Lyme disease supports further recent evidence that this illness is an infectious
disease caused by a tick-borne bacterium. The skin biopsy may be a useful diagnostic tool in this
disease.

Am J Med Sci. 1984 Mar-Apr;287(2):40-2. Case Reports

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