Editor’s Note: This study highlights the fact that most people with Lyme disease do not recall a tick bite or bulls-eye rash; therefore, better diagnostic tools are needed to diagnose Lyme disease, especially since, in the later stages of illness, most Western Blot, Elisa and other blood tests come out negative, due to the body’s inability to mount an antibody response to them, the absence of the pathogen in the blood, and the fact that tests have not yet been developed for all strains of Borrelia that infect humans and cause disease.
A minority of children diagnosed with Lyme disease recall a preceding tick bite
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Of 1770 children undergoing emergency department evaluation for Lyme disease, 362 (20.5%) children had Lyme disease. Of those with an available tick bite history, only a minority of those with Lyme disease had a recognized tick bite (60/325; 18.5%, 95% confidence interval 14.6-23.0%). Lack of a tick bite history does not reliably exclude Lyme disease.
Source: By Nigrovic LE1, Neville DN2, Balamuth F3, Bennett JE4, Levas MN5, Garro AC6; A minority of children diagnosed with Lyme disease recall a preceding tick bite. Ticks Tick Borne Dis. 2019 Feb 26. pii: S1877-959X(18)30496-5. doi: 10.1016/j.ttbdis.2019.02.015. [Epub ahead of print] for Pedi Lyme Net.