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Pseudotumor cerebri in Lyme disease: a case report and literature review.

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Pseudotumor cerebri is an unusual presentation of
Lyme disease. The case of an 8-year-old girl with pseudotumor cerebri secondary to acute neuroborreliosis is reported. She presented with acute onset of headache, papilledema, sixth nerve palsy, increased intracranial pressure, and cerebrospinal fluid pleocytosis. Serum and cerebrospinal fluid
Lyme antibodies were positive. Twelve reported cases that mostly presented with systemic findings and signs of
Lyme disease before development of pseudotumor cerebri were reviewed. We conclude that acute neuroborreliosis can present with pseudotumor cerebri as an initial manifestation. It is important to include
Lyme disease in the differential diagnosis of pseudotumor cerebri in an area endemic for
Lyme disease.

Pediatr Neurol. 1998 May;18(5):439-41. Case Reports; Review

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