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The etiology of uveitis: the role of infections with special reference to Lyme borreliosis.

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Abstract

PURPOSE:

To assess the distribution of different uveitis entities and to evaluate their associations with infections, especially
Lyme borreliosis.

METHODS:

During a one-year period 160 consecutive uveitis patients were evaluated in a university clinic. Selected tests were performed depending on the medical history of the patient and the clinical picture of the ocular inflammation.

RESULTS:

Uveitis was classified into selected entities for 74.4% of the patients. A direct infection was suggested to be linked with uveitis in 23 patients (14.4%).
Lyme borreliosis, toxoplasmosis, and herpetic infections were the most frequently seen, in seven patients (4.3%) each. All patients with
Lyme uveitis had manifestations of the posterior segment of the eye, such as vitritis, retinal vasculitis, neuroretinitis, chorioretinitis, or optic neuropathy.

CONCLUSION:

Infections are an important cause of uveitis in a university clinic.
Lyme borreliosis is a newly recognised uveitis entity which should be kept in mind in the differential diagnosis of intermediate or posterior uveitis in areas endemic for
Lyme borreliosis.

Acta Ophthalmol Scand. 1997 Dec;75(6):716-9. Research Support, Non-U.S. Gov’t

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