BACKGROUND: Chronic Fatigue syndrome (CFS) is a relatively newly
defined clinical entity that affects multiple systems
including the ocular system. These effects have not been well
METHODS: 25 consecutive CFS patients were
evaluated and the ocular signs and symptoms were described.
RESULTS: Significant ocular symptoms were present in all 25
patients. The most common clinical findings were abnormalities
of the preocular tear film and ocular surface (19 patients)
and reduced accommodation for age (18 patients).
CFS affects the ocular system in many ways. Eye care
practitioners should pay particular attention to accommodative
needs, ocular surface disease and tear film dysfunction when
examining these patients. Further research into the
pathophysiology of these ocular findings may lead to a better
understanding of the pathophysiology of CFS.
MCM: A flawed article but showed rose bengal corneal staining
mod-severe in 26 of 50 eyes, ll/15 had “lower than minimal”
accomodation, most eyes (31/?44) had abnormal Schirmer.Of 25
pts, 9 complained of dryness, 8 of scratchiness, 4 of
Caffery BE, Josephson JE, Samek MJ