Therapeutic program reverses cognitive decline

1 Star2 Stars3 Stars4 Stars5 Stars (6 votes, average: 5.00 out of 5)
Loading...
Reprinted with the kind permission of Life Extension.

May 13 2015. The September 2014 issue of Aging contains an article by Dale E. Bredesen, MD, of the University of California, Los Angeles which reviews the effects of a multimodal personalized program designed for patients with Alzheimer's disease, amnestic mild cognitive impairment or subjective cognitive impairment. The program, which consists of the intake of a number of targeted nutrients, optimized hormone balance, exercise, a low glycemic diet, stress reduction, brain stimulation, sleep optimization and other factors, was found to benefit the ten subjects who took part in it, with the exception of one participant with late stage Alzheimer's disease.
 
Nutritional supplements administered over the course of the program included methylcobalamin, methyltetrahydrofolate, pyridoxal-5'-phosphate, TMG, prebiotics, probiotics, curcumin, ashwagandha, Bacopa monniera, magnesium threonate, vitamin D3, vitamin K2, acetyl-L-carnitine, citicholine, EPA/DHA, mixed tocopherols and tocotrienols; selenium, blueberries, N-acetylcysteine, ascorbate, alpha-lipoic acid, CoQ10, PQQ, resveratrol, thiamine, pantothenic acid. Of six participants whose cognitive impairment had impacted their ability to work, all were able to return to work or continue working at their jobs with improved performance after following the program.
 
"The positive results reported here are perhaps not surprising given that therapeutic programs have proven more effective than monotherapeutics in multiple chronic illnesses, such as atherosclerotic cardiovascular disease, HIV, and cancer," notes Dr Bredesen, of UCLA's Mary S. Easton Center for Alzheimer's Disease Research. "Indeed, chronic illnesses may be more amenable to therapeutic systems than to monotherapeutics."
 
"The current, anecdotal results require a larger trial, not only to confirm or refute the results reported here, but also to address key questions raised, such as the degree of improvement that can be achieved routinely, how late in the course of cognitive decline reversal can be effected, whether such an approach may be effective in patients with familial Alzheimer’s disease, and how long improvement can be sustained," he concludes.
ADVERTISEMENT




1 Star2 Stars3 Stars4 Stars5 Stars (6 votes, average: 5.00 out of 5)
Loading...



Leave a Reply