Using a novel algorithm, researchers find that a pro-inflammatory diet increases the risk of frailty by 16% — and that the least inflammatory diets fight this decline in physical function. 

NMN supplementation promoted healthier aging in mice by altering the metabolism of amino acids, nucleotides, and NAD+, in addition to lengthening chromosomal ends called telomeres.

Declining NAD+ is implicated in age-related bone loss. Repleting NAD+ with one of its precursors, nicotinamide riboside (NR), restores youthful bones and attenuates bone loss in aging female mice.

Maintaining mentally challenging employment benefits cognition and wellbeing among older adults — especially when combined with social connectedness and a sense of purpose.