Berberine is a compound produced by several plants; this study finds low-dose berberine increases lifespan in yeast, mice, and human cells and reverses biomarkers of aging.

The compound oleuropein, found in olives, could have strong therapeutic potential for people with disorders related to joints, cartilage, and bones.

In older adults, vaccines are generally less effective, and why this happens remains largely unknown. This study finds that spermidine may be used to improve vaccination efficiency in older adults.

Cells treated with NMN after glucocorticoid exposure had improved bone-building markers, indicating that NMN may be a useful therapy to protect against bone loss in people taking glucocorticoids.