Lifelong high-volume exercise training increases mitochondrial function by increasing mitochondrial volume, likely contributing to healthy aging.

Exercising mice produce more of a selenium-shuttling protein that encourages new neuron growth and supports memory and learning even amongst the oldest animals.

Caloric restriction (CR) activates a core gene activity program that promotes immune function, reduces inflammation, and reveals a potential mechanism to mimic the beneficial effects of CR.

Superagers have the longevity genes to help them age superbly, but it's their epigenetic changes made by specific lifestyle choices that account for an estimated 80% of the battle.